1mly: Difference between revisions

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[[Image:1mly.gif|left|200px]]<br /><applet load="1mly" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1mly.gif|left|200px]]
caption="1mly, resolution 1.81&Aring;" />
 
'''Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin'''<br />
{{Structure
|PDB= 1mly |SIZE=350|CAPTION= <scene name='initialview01'>1mly</scene>, resolution 1.81&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACZ:CIS-AMICLENOMYCIN'>ACZ</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62]
|GENE= bioA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1MLY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ACZ:'>ACZ</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLY OCA].  
1MLY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MLY OCA].  


==Reference==
==Reference==
Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin., Sandmark J, Mann S, Marquet A, Schneider G, J Biol Chem. 2002 Nov 8;277(45):43352-8. Epub 2002 Sep 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12218056 12218056]
Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin., Sandmark J, Mann S, Marquet A, Schneider G, J Biol Chem. 2002 Nov 8;277(45):43352-8. Epub 2002 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12218056 12218056]
[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: subclass ii]]
[[Category: subclass ii]]


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