3pdi: Difference between revisions
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[[ | ==Precursor bound NifEN== | ||
<StructureSection load='3pdi' size='340' side='right' caption='[[3pdi]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pdi]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PDI FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CZL:L-CLUSTER+(FE8S9)'>CZL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Avin_01450, nifE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 Azotobacter vinelandii]), Avin_01470, nifN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 Azotobacter vinelandii])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pdi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pdi RCSB], [http://www.ebi.ac.uk/pdbsum/3pdi PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
NifEN plays an essential role in the biosynthesis of the nitrogenase iron-molybdenum (FeMo) cofactor (M cluster). It is an alpha(2)beta(2) tetramer that is homologous to the catalytic molybdenum-iron (MoFe) protein (NifDK) component of nitrogenase. NifEN serves as a scaffold for the conversion of an iron-only precursor to a matured form of the M cluster before delivering the latter to its target location within NifDK. Here, we present the structure of the precursor-bound NifEN of Azotobacter vinelandii at 2.6 angstrom resolution. From a structural comparison of NifEN with des-M-cluster NifDK and holo NifDK, we propose similar pathways of cluster insertion for the homologous NifEN and NifDK proteins. | |||
Structure of precursor-bound NifEN: a nitrogenase FeMo cofactor maturase/insertase.,Kaiser JT, Hu Y, Wiig JA, Rees DC, Ribbe MW Science. 2011 Jan 7;331(6013):91-4. PMID:21212358<ref>PMID:21212358</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
==See Also== | ==See Also== | ||
*[[Nitrogenase|Nitrogenase]] | *[[Nitrogenase|Nitrogenase]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Azotobacter vinelandii]] | [[Category: Azotobacter vinelandii]] | ||
[[Category: Hu, Y | [[Category: Hu, Y]] | ||
[[Category: Kaiser, J T | [[Category: Kaiser, J T]] | ||
[[Category: Rees, D C | [[Category: Rees, D C]] | ||
[[Category: Ribbe, M W | [[Category: Ribbe, M W]] | ||
[[Category: Wiig, J A | [[Category: Wiig, J A]] | ||
[[Category: Nifb]] | [[Category: Nifb]] | ||
[[Category: Nifdk]] | [[Category: Nifdk]] | ||
