1n0t: Difference between revisions

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[[Image:1n0t.jpg|left|200px]]<br /><applet load="1n0t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1n0t.jpg|left|200px]]
caption="1n0t, resolution 2.10&Aring;" />
 
'''X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.'''<br />
{{Structure
|PDB= 1n0t |SIZE=350|CAPTION= <scene name='initialview01'>1n0t</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=AT1:(S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID'>AT1</scene>
|ACTIVITY=
|GENE= Rat ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1N0T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=AT1:'>AT1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0T OCA].  
1N0T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0T OCA].  


==Reference==
==Reference==
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX., Hogner A, Greenwood JR, Liljefors T, Lunn ML, Egebjerg J, Larsen IK, Gouaux E, Kastrup JS, J Med Chem. 2003 Jan 16;46(2):214-21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12519060 12519060]
Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX., Hogner A, Greenwood JR, Liljefors T, Lunn ML, Egebjerg J, Larsen IK, Gouaux E, Kastrup JS, J Med Chem. 2003 Jan 16;46(2):214-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12519060 12519060]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ligand-binding core]]
[[Category: ligand-binding core]]


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