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[[Image:2ogd.png|left|200px]]
==T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527==
 
<StructureSection load='2ogd' size='340' side='right' caption='[[2ogd]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
{{STRUCTURE_2ogd|  PDB=2ogd  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ogd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGD FirstGlance]. <br>
===T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SUF:[2-(DIMETHYL-LAMBDA~4~-SULFANYL)-1-HYDROXYETHANE-1,1-DIYL]BIS(PHOSPHONIC+ACID)'>SUF</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ogc|2ogc]], [[2ogl|2ogl]]</td></tr>
 
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] </span></td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ogd RCSB], [http://www.ebi.ac.uk/pdbsum/2ogd PDBsum]</span></td></tr>
[[2ogd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGD OCA].  
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
__TOC__
</StructureSection>
[[Category: Geranyltranstransferase]]
[[Category: Geranyltranstransferase]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]

Revision as of 06:25, 29 September 2014

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527

2ogd, resolution 2.00Å

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