2i96: Difference between revisions
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{{STRUCTURE_2i96| PDB=2i96 | SCENE= }} | {{STRUCTURE_2i96| PDB=2i96 | SCENE= }} | ||
===Solution structure of the oxidized microsomal human cytochrome b5=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CYB5_HUMAN CYB5_HUMAN]] Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:[http://omim.org/entry/250790 250790]]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.<ref>PMID:8168836</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CYB5_HUMAN CYB5_HUMAN]] Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Cytochrome b5|Cytochrome b5]] | *[[Cytochrome b5|Cytochrome b5]] | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Heijenoort, C Van.]] | [[Category: Heijenoort, C Van.]] | ||
Revision as of 06:12, 25 March 2013
Solution structure of the oxidized microsomal human cytochrome b5
Disease
[CYB5_HUMAN] Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.[1]
Function
[CYB5_HUMAN] Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
About this Structure
2i96 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
