1ndn: Difference between revisions
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[[Image:1ndn.jpg|left|200px]] | [[Image:1ndn.jpg|left|200px]] | ||
'''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4''' | {{Structure | ||
|PDB= 1ndn |SIZE=350|CAPTION= <scene name='initialview01'>1ndn</scene>, resolution 3.000Å | |||
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'''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1NDN is a [ | 1NDN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA]. | ||
==Reference== | ==Reference== | ||
Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:[http:// | Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2320572 2320572] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Aymani, J.]] | [[Category: Aymani, J.]] | ||
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[[Category: nicked]] | [[Category: nicked]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:55:30 2008'' | ||
Revision as of 10:55, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4
Overview
The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.
About this Structure
1NDN is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:2320572
Page seeded by OCA on Thu Mar 20 12:55:30 2008
