1ndz: Difference between revisions

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[[Image:1ndz.jpg|left|200px]]<br /><applet load="1ndz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ndz.jpg|left|200px]]
caption="1ndz, resolution 2.&Aring;" />
 
'''Crystal Structure of Adenosine Deaminase Complexed with FR235999'''<br />
{{Structure
|PDB= 1ndz |SIZE=350|CAPTION= <scene name='initialview01'>1ndz</scene>, resolution 2.&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=FR5:1-((1R)-1-(HYDROXYMETHYL)-3-(6-((3-(1-METHYL-1H-BENZIMIDAZOL-2-YL)PROPANOYL)AMINO)-1H-INDOL-1-YL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE'>FR5</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4]
|GENE=
}}
 
'''Crystal Structure of Adenosine Deaminase Complexed with FR235999'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NDZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=FR5:'>FR5</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDZ OCA].  
1NDZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDZ OCA].  


==Reference==
==Reference==
A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization., Terasaka T, Kinoshita T, Kuno M, Nakanishi I, J Am Chem Soc. 2004 Jan 14;126(1):34-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14709046 14709046]
A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization., Terasaka T, Kinoshita T, Kuno M, Nakanishi I, J Am Chem Soc. 2004 Jan 14;126(1):34-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14709046 14709046]
[[Category: Adenosine deaminase]]
[[Category: Adenosine deaminase]]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: tim-barrel]]
[[Category: tim-barrel]]


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