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[[Image:1z8f.png|left|200px]]
==Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)==
 
<StructureSection load='1z8f' size='340' side='right' caption='[[1z8f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
{{STRUCTURE_1z8f|  PDB=1z8f  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1z8f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8F FirstGlance]. <br>
===Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s4q|1s4q]]</td></tr>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
[[1z8f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8F OCA].  
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8f RCSB], [http://www.ebi.ac.uk/pdbsum/1z8f PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/1z8f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Guanylate kinase|Guanylate kinase]]
*[[Guanylate kinase|Guanylate kinase]]
__TOC__
</StructureSection>
[[Category: Guanylate kinase]]
[[Category: Guanylate kinase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

Revision as of 21:42, 28 September 2014

Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)

1z8f, resolution 2.50Å

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