1nma: Difference between revisions

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[[Image:1nma.gif|left|200px]]<br /><applet load="1nma" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nma.gif|left|200px]]
caption="1nma, resolution 3.0&Aring;" />
 
'''N9 NEURAMINIDASE COMPLEXES WITH ANTIBODIES NC41 AND NC10: EMPIRICAL FREE-ENERGY CALCULATIONS CAPTURE SPECIFICITY TRENDS OBSERVED WITH MUTANT BINDING DATA'''<br />
{{Structure
|PDB= 1nma |SIZE=350|CAPTION= <scene name='initialview01'>1nma</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18]
|GENE=
}}
 
'''N9 NEURAMINIDASE COMPLEXES WITH ANTIBODIES NC41 AND NC10: EMPIRICAL FREE-ENERGY CALCULATIONS CAPTURE SPECIFICITY TRENDS OBSERVED WITH MUTANT BINDING DATA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NMA is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Influenza_virus_a/whale/maine/1/84_isolated_from_pilot_whale_(globicephala_melaena) Influenza virus a/whale/maine/1/84 isolated from pilot whale (globicephala melaena)] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NMA OCA].  
1NMA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Influenza_virus_a/whale/maine/1/84_isolated_from_pilot_whale_(globicephala_melaena) Influenza virus a/whale/maine/1/84 isolated from pilot whale (globicephala melaena)] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NMA OCA].  


==Reference==
==Reference==
N9 neuraminidase complexes with antibodies NC41 and NC10: empirical free energy calculations capture specificity trends observed with mutant binding data., Tulip WR, Harley VR, Webster RG, Novotny J, Biochemistry. 1994 Jul 5;33(26):7986-97. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7517697 7517697]
N9 neuraminidase complexes with antibodies NC41 and NC10: empirical free energy calculations capture specificity trends observed with mutant binding data., Tulip WR, Harley VR, Webster RG, Novotny J, Biochemistry. 1994 Jul 5;33(26):7986-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7517697 7517697]
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Influenza virus a/whale/maine/1/84 isolated from pilot whale (globicephala melaena)]]
[[Category: Influenza virus a/whale/maine/1/84 isolated from pilot whale (globicephala melaena)]]
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[[Category: complex (hydrolase/immunoglobulin)]]
[[Category: complex (hydrolase/immunoglobulin)]]


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