1nq2: Difference between revisions

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[[Image:1nq2.jpg|left|200px]]<br /><applet load="1nq2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nq2.jpg|left|200px]]
caption="1nq2, resolution 2.4&Aring;" />
 
'''Two RTH Mutants with Impaired Hormone Binding'''<br />
{{Structure
|PDB= 1nq2 |SIZE=350|CAPTION= <scene name='initialview01'>1nq2</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC+ACID'>4HY</scene> and <scene name='pdbligand=ARS:ARSENIC'>ARS</scene>
|ACTIVITY=
|GENE= THRB OR NR1A2 OR ERBA2 OR THR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Two RTH Mutants with Impaired Hormone Binding'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NQ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=4HY:'>4HY</scene> and <scene name='pdbligand=ARS:'>ARS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ2 OCA].  
1NQ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ2 OCA].  


==Reference==
==Reference==
Two resistance to thyroid hormone mutants with impaired hormone binding., Huber BR, Sandler B, West BL, Cunha Lima ST, Nguyen HT, Apriletti JW, Baxter JD, Fletterick RJ, Mol Endocrinol. 2003 Apr;17(4):643-52. Epub 2003 Jan 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12554782 12554782]
Two resistance to thyroid hormone mutants with impaired hormone binding., Huber BR, Sandler B, West BL, Cunha Lima ST, Nguyen HT, Apriletti JW, Baxter JD, Fletterick RJ, Mol Endocrinol. 2003 Apr;17(4):643-52. Epub 2003 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12554782 12554782]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ligand binding domain]]
[[Category: ligand binding domain]]


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