1m4a: Difference between revisions
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{{STRUCTURE_1m4a| PDB=1m4a | SCENE= }} | {{STRUCTURE_1m4a| PDB=1m4a | SCENE= }} | ||
===Crystal Structure of Human Interleukin-2 Y31C Covalently Modified at C31 with (1H-Indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid=== | |||
{{ABSTRACT_PUBMED_12582206}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN]] Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN]] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012582206</ref><ref group="xtra">PMID:012767230</ref><references group="xtra"/> | <ref group="xtra">PMID:012582206</ref><ref group="xtra">PMID:012767230</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arkin, M A.]] | [[Category: Arkin, M A.]] | ||
