1nug: Difference between revisions

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[[Image:1nug.gif|left|200px]]<br /><applet load="1nug" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nug.gif|left|200px]]
caption="1nug, resolution 2.40&Aring;" />
 
'''Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form)'''<br />
{{Structure
|PDB= 1nug |SIZE=350|CAPTION= <scene name='initialview01'>1nug</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13]
|GENE= TGM3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NUG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-glutamine_gamma-glutamyltransferase Protein-glutamine gamma-glutamyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.13 2.3.2.13] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NUG OCA].  
1NUG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NUG OCA].  


==Reference==
==Reference==
Roles of calcium ions in the activation and activity of the transglutaminase 3 enzyme., Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM, J Biol Chem. 2003 Jun 27;278(26):23834-41. Epub 2003 Apr 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12679341 12679341]
Roles of calcium ions in the activation and activity of the transglutaminase 3 enzyme., Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM, J Biol Chem. 2003 Jun 27;278(26):23834-41. Epub 2003 Apr 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12679341 12679341]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-glutamine gamma-glutamyltransferase]]
[[Category: Protein-glutamine gamma-glutamyltransferase]]
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[[Category: x-ray crystallography]]
[[Category: x-ray crystallography]]


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