3h2v: Difference between revisions

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[[Image:3h2v.png|left|200px]]
{{STRUCTURE_3h2v|  PDB=3h2v  |  SCENE=  }}  
{{STRUCTURE_3h2v|  PDB=3h2v  |  SCENE=  }}  
===Human raver1 RRM1 domain in complex with human vinculin tail domain Vt===
===Human raver1 RRM1 domain in complex with human vinculin tail domain Vt===
{{ABSTRACT_PUBMED_19523901}}


{{ABSTRACT_PUBMED_19523901}}
==Function==
[[http://www.uniprot.org/uniprot/RAVR1_HUMAN RAVR1_HUMAN]] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:019523901</ref><references group="xtra"/>
<ref group="xtra">PMID:019523901</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Izard, T.]]
[[Category: Izard, T.]]

Revision as of 23:42, 24 March 2013

Template:STRUCTURE 3h2v

Human raver1 RRM1 domain in complex with human vinculin tail domain Vt

Template:ABSTRACT PUBMED 19523901

Function

[RAVR1_HUMAN] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).

About this Structure

3h2v is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lee JH, Rangarajan ES, Yogesha SD, Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure. 2009 Jun 10;17(6):833-42. PMID:19523901 doi:S0969-2126(09)00193-2

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