3cfs: Difference between revisions
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{{STRUCTURE_3cfs| PDB=3cfs | SCENE= }} | {{STRUCTURE_3cfs| PDB=3cfs | SCENE= }} | ||
===Structural basis of the interaction of RbAp46/RbAp48 with histone H4=== | ===Structural basis of the interaction of RbAp46/RbAp48 with histone H4=== | ||
{{ABSTRACT_PUBMED_18571423}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RBBP7_HUMAN RBBP7_HUMAN]] Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018571423</ref><references group="xtra"/> | <ref group="xtra">PMID:018571423</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ben-Shahar, T R.]] | [[Category: Ben-Shahar, T R.]] | ||
