1o0j: Difference between revisions

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~~{{Theoretical_model}}~~

==HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE==

== Structural highlights ==

<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O0J FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o0j FirstGlance], [http://www.ebi.ac.uk/pdbsum/1o0j PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain residues at the C-terminus that are absent in the other proteases. We have prepared a mutant of HTLV-I protease that does not contain the 10 C-terminal residues and demonstrated that the catalytic efficiency of cleavage of a peptide substrate is unaffected.

~~[[Image~~:~~1o0j~~.~~png|left|200px]]~~

The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.,Herger BE, Mariani VL, Dennison K, Shuker SB Biochem Biophys Res Commun. 2004 Aug 6;320(4):1306-8. PMID:15303275<ref>PMID:15303275</ref>

~~{{STRUCTURE_1o0j| PDB=1o0j | SCENE= }}~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~===HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID~~/~~NUCLEOCAPSID (CA/NC) SUBSTRATE===~~

== References ==

~~{{ABSTRACT_PUBMED_15303275}}~~

__TOC__

</StructureSection>

==~~Reference~~==

<~~ref group="xtra">PMID:015303275<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Dennison, K]]

[[Category: Herger, B E]]

[[Category: Shuker, S B]]

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@@ Line 1: / Line 1: @@
-{{Theoretical_model}}
+==HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE==
+<StructureSection load='1o0j' size='340' side='right' caption='[[1o0j]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O0J FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o0j FirstGlance], [http://www.ebi.ac.uk/pdbsum/1o0j PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain residues at the C-terminus that are absent in the other proteases. We have prepared a mutant of HTLV-I protease that does not contain the 10 C-terminal residues and demonstrated that the catalytic efficiency of cleavage of a peptide substrate is unaffected.
-[[Image:1o0j.png|left|200px]]
+The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.,Herger BE, Mariani VL, Dennison K, Shuker SB Biochem Biophys Res Commun. 2004 Aug 6;320(4):1306-8. PMID:15303275<ref>PMID:15303275</ref>
-{{STRUCTURE_1o0j|  PDB=1o0j  |  SCENE=  }}
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-===HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE===
+== References ==
+<references/>
-{{ABSTRACT_PUBMED_15303275}}
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:015303275</ref><references group="xtra"/>
 [[Category: Dennison, K]]
 [[Category: Herger, B E]]
 [[Category: Shuker, S B]]