1eu0: Difference between revisions

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~~{{Theoretical_model}}~~

==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)==

== Structural highlights ==

<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EU0 FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eu0 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eu0 PDBsum]</span></td></tr>

<table>

== Publication Abstract from PubMed ==

Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification.

~~[[Image~~:~~1eu0~~.~~png|left|200px]]~~

alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref>

~~{{STRUCTURE_1eu0| PDB=1eu0 | SCENE= }}~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~===THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT~~, ~~FROM 312 TO 361 POSITION)===~~

== References ==

~~{{ABSTRACT_PUBMED_10812058}}~~

__TOC__

</StructureSection>

==~~Reference~~==

<~~ref group="xtra">PMID:010812058<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Kajava, A V]]

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@@ Line 1: / Line 1: @@
-{{Theoretical_model}}
+==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)==
+<StructureSection load='1eu0' size='340' side='right' caption='[[1eu0]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EU0 FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eu0 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eu0 PDBsum]</span></td></tr>
+<table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification.
-[[Image:1eu0.png|left|200px]]
+alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref>
-{{STRUCTURE_1eu0|  PDB=1eu0  |  SCENE=  }}
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-===THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)===
+== References ==
+<references/>
-{{ABSTRACT_PUBMED_10812058}}
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:010812058</ref><references group="xtra"/>
 [[Category: Kajava, A V]]