1oe0: Difference between revisions

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[[Image:1oe0.jpg|left|200px]]<br /><applet load="1oe0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1oe0.jpg|left|200px]]
caption="1oe0, resolution 2.40&Aring;" />
 
'''CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP'''<br />
{{Structure
|PDB= 1oe0 |SIZE=350|CAPTION= <scene name='initialview01'>1oe0</scene>, resolution 2.40&Aring;
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=TTP:THYMIDINE-5'-TRIPHOSPHATE'>TTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OE0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=TTP:'>TTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] Known structural/functional Site: <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OE0 OCA].  
1OE0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OE0 OCA].  


==Reference==
==Reference==
Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyribonucleoside kinase., Mikkelsen NE, Johansson K, Karlsson A, Knecht W, Andersen G, Piskur J, Munch-Petersen B, Eklund H, Biochemistry. 2003 May 20;42(19):5706-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12741827 12741827]
Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyribonucleoside kinase., Mikkelsen NE, Johansson K, Karlsson A, Knecht W, Andersen G, Piskur J, Munch-Petersen B, Eklund H, Biochemistry. 2003 May 20;42(19):5706-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12741827 12741827]
[[Category: Deoxynucleoside kinase]]
[[Category: Deoxynucleoside kinase]]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: salvage pathway]]
[[Category: salvage pathway]]


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