1okv: Difference between revisions

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[[Image:1okv.gif|left|200px]]<br /><applet load="1okv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1okv.gif|left|200px]]
caption="1okv, resolution 2.40&Aring;" />
 
'''CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ILE-PHE-NH2'''<br />
{{Structure
|PDB= 1okv |SIZE=350|CAPTION= <scene name='initialview01'>1okv</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ILE-PHE-NH2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OKV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OKV OCA].  
1OKV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OKV OCA].  


==Reference==
==Reference==
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14656438 14656438]
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14656438 14656438]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: NH2]]
[[Category: NH2]]
[[Category: cell cycle]]
[[Category: cell cycle]]
[[Category: cyclin a]]
[[Category: cyclin some]]
[[Category: drug design]]
[[Category: drug design]]
[[Category: inhibitor]]
[[Category: inhibitor]]
[[Category: kinase]]
[[Category: kinase]]
[[Category: ligand exchange]]
[[Category: ligand exchange]]
[[Category: peptidomimetics]]
[[Category: peptidomimetic]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:18:51 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:12:16 2008''
Retrieved from "https://proteopedia.org/1okv"