1osh: Difference between revisions

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[[Image:1osh.jpg|left|200px]]~~<br /><applet load~~="1osh~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1osh.jpg|left|200px]]

~~caption="~~1osh, resolution 1.80Å" />

'''A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR'''~~<br />~~

{{Structure

|PDB= 1osh |SIZE=350|CAPTION= <scene name='initialview01'>1osh</scene>, resolution 1.80Å

|SITE=

|LIGAND= <scene name='pdbligand=FEX:METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE'>FEX</scene>

|ACTIVITY=

|GENE= NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR'''

==Overview==

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Line 19:

==About this Structure==

1OSH is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=FEX:'>FEX</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSH OCA].

1OSH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSH OCA].

==Reference==

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR., Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM, Mol Cell. 2003 Apr;11(4):1079-92. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~12718892 12718892]

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR., Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM, Mol Cell. 2003 Apr;11(4):1079-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12718892 12718892]

[[Category: Homo sapiens]]

[[Category: Single protein]]

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[[Category: nuclear receptor]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:15:02 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1osh.jpg|left|200px]]<br /><applet load="1osh" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1osh.jpg|left|200px]]
-caption="1osh, resolution 1.80&Aring;" />
-'''A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR'''<br />
+ {{Structure
+|PDB= 1osh |SIZE=350|CAPTION= <scene name='initialview01'>1osh</scene>, resolution 1.80&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=FEX:METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE'>FEX</scene>
+|ACTIVITY=
+|GENE= NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-OSH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FEX:'>FEX</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSH OCA].
+OSH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OSH OCA].
 ==Reference==
-A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR., Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM, Mol Cell. 2003 Apr;11(4):1079-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12718892 12718892]
+A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR., Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM, Mol Cell. 2003 Apr;11(4):1079-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12718892 12718892]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 35: / Line 44: @@
 [[Category: nuclear receptor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:21:08 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:15:02 2008''