1ot7: Difference between revisions

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[[Image:1ot7.gif|left|200px]]<br /><applet load="1ot7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ot7.gif|left|200px]]
caption="1ot7, resolution 2.90&Aring;" />
 
'''Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR'''<br />
{{Structure
|PDB= 1ot7 |SIZE=350|CAPTION= <scene name='initialview01'>1ot7</scene>, resolution 2.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=IU5:ISO-URSODEOXYCHOLIC+ACID'>IU5</scene> and <scene name='pdbligand=CHC:6-ETHYL-CHENODEOXYCHOLIC ACID'>CHC</scene>
|ACTIVITY=
|GENE= NR1H4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OT7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=IU5:'>IU5</scene> and <scene name='pdbligand=CHC:'>CHC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OT7 OCA].  
1OT7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OT7 OCA].  


==Reference==
==Reference==
Structural basis for bile acid binding and activation of the nuclear receptor FXR., Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, Khorasanizadeh S, Rastinejad F, Mol Cell. 2003 Apr;11(4):1093-100. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12718893 12718893]
Structural basis for bile acid binding and activation of the nuclear receptor FXR., Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, Khorasanizadeh S, Rastinejad F, Mol Cell. 2003 Apr;11(4):1093-100. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12718893 12718893]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: nuclear receptor]]
[[Category: nuclear receptor]]


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Retrieved from "https://proteopedia.org/1ot7"