1otx: Difference between revisions

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[[Image:1otx.gif|left|200px]]<br /><applet load="1otx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1otx.gif|left|200px]]
caption="1otx, resolution 2.70&Aring;" />
 
'''Purine Nucleoside Phosphorylase M64V mutant'''<br />
{{Structure
|PDB= 1otx |SIZE=350|CAPTION= <scene name='initialview01'>1otx</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
|GENE=
}}
 
'''Purine Nucleoside Phosphorylase M64V mutant'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OTX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTX OCA].  
1OTX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTX OCA].  


==Reference==
==Reference==
Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system., Bennett EM, Anand R, Allan PW, Hassan AE, Hong JS, Levasseur DN, McPherson DT, Parker WB, Secrist JA 3rd, Sorscher EJ, Townes TM, Waud WR, Ealick SE, Chem Biol. 2003 Dec;10(12):1173-81. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14700625 14700625]
Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system., Bennett EM, Anand R, Allan PW, Hassan AE, Hong JS, Levasseur DN, McPherson DT, Parker WB, Secrist JA 3rd, Sorscher EJ, Townes TM, Waud WR, Ealick SE, Chem Biol. 2003 Dec;10(12):1173-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14700625 14700625]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
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[[Category: pnp]]
[[Category: pnp]]


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