1cjb: Difference between revisions

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Revision as of 20:07, 21 October 2012

File:1cjb.png

Template:STRUCTURE 1cjb

MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE

Template:ABSTRACT PUBMED 10433693

About this Structure

1cjb is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  1. Shi W, Li CM, Tyler PC, Furneaux RH, Cahill SM, Girvin ME, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor. Biochemistry. 1999 Aug 3;38(31):9872-80. PMID:10433693 doi:10.1021/bi990664p
  2. Joshi AA, Viswanathan CL. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials. Bioorg Med Chem Lett. 2006 May 15;16(10):2613-7. Epub 2006 Mar 3. PMID:16516468 doi:10.1016/j.bmcl.2006.02.038

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