1ov4: Difference between revisions

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[[Image:1ov4.jpg|left|200px]]<br /><applet load="1ov4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ov4.jpg|left|200px]]
caption="1ov4, resolution 2.7&Aring;" />
 
'''Crystal structure of human DHEA-ST complexed with androsterone'''<br />
{{Structure
|PDB= 1ov4 |SIZE=350|CAPTION= <scene name='initialview01'>1ov4</scene>, resolution 2.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=AE2:AETIOCHOLANOLONE'>AE2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_sulfotransferase Alcohol sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.2 2.8.2.2]
|GENE= SULT2A1 OR STD OR HST ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human DHEA-ST complexed with androsterone'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OV4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=AE2:'>AE2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_sulfotransferase Alcohol sulfotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.2.2 2.8.2.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OV4 OCA].  
1OV4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OV4 OCA].  


==Reference==
==Reference==
Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex., Chang HJ, Shi R, Rehse P, Lin SX, J Biol Chem. 2004 Jan 23;279(4):2689-96. Epub 2003 Oct 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14573603 14573603]
Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex., Chang HJ, Shi R, Rehse P, Lin SX, J Biol Chem. 2004 Jan 23;279(4):2689-96. Epub 2003 Oct 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14573603 14573603]
[[Category: Alcohol sulfotransferase]]
[[Category: Alcohol sulfotransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: alpha/beta fold]]
[[Category: alpha/beta fold]]


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