1ozs: Difference between revisions

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[[Image:1ozs.jpg|left|200px]]<br /><applet load="1ozs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ozs.jpg|left|200px]]
caption="1ozs" />
 
'''C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I'''<br />
{{Structure
|PDB= 1ozs |SIZE=350|CAPTION= <scene name='initialview01'>1ozs</scene>
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=  
|GENE= TNNC1 OR TNNC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), TNNI3 OR TNNC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: Cardiomyopathy, familial hypertrophic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191044 191044]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial restrictive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191044 191044]]
Known diseases associated with this structure: Cardiomyopathy, dilated, 1Z OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, dilated, 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191044 191044]], Cardiomyopathy, familial hypertrophic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191044 191044]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial restrictive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191044 191044]]


==About this Structure==
==About this Structure==
1OZS is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OZS OCA].  
1OZS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OZS OCA].  


==Reference==
==Reference==
Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I., Lindhout DA, Sykes BD, J Biol Chem. 2003 Jul 18;278(29):27024-34. Epub 2003 May 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12732641 12732641]
Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I., Lindhout DA, Sykes BD, J Biol Chem. 2003 Jul 18;278(29):27024-34. Epub 2003 May 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12732641 12732641]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: ef-hand]]
[[Category: ef-hand]]


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