1p14: Difference between revisions

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[[Image:1p14.gif|left|200px]]<br /><applet load="1p14" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p14.gif|left|200px]]
caption="1p14, resolution 1.90&Aring;" />
 
'''Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase'''<br />
{{Structure
|PDB= 1p14 |SIZE=350|CAPTION= <scene name='initialview01'>1p14</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE=
}}
 
'''Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1P14 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P14 OCA].  
1P14 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P14 OCA].  


==Reference==
==Reference==
Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor., Li S, Covino ND, Stein EG, Till JH, Hubbard SR, J Biol Chem. 2003 Jul 11;278(28):26007-14. Epub 2003 Apr 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12707268 12707268]
Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor., Li S, Covino ND, Stein EG, Till JH, Hubbard SR, J Biol Chem. 2003 Jul 11;278(28):26007-14. Epub 2003 Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12707268 12707268]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tyrosine kinase]]
[[Category: tyrosine kinase]]


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