1cf1: Difference between revisions
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{{STRUCTURE_1cf1| PDB=1cf1 | SCENE= }} | {{STRUCTURE_1cf1| PDB=1cf1 | SCENE= }} | ||
===ARRESTIN FROM BOVINE ROD OUTER SEGMENTS=== | |||
{{ABSTRACT_PUBMED_10219246}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Note=S-antigen induces autoimmune uveitis. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010219246</ref><references group="xtra"/> | <ref group="xtra">PMID:010219246</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Gurevich, V V.]] | [[Category: Gurevich, V V.]] | ||
Revision as of 03:03, 25 March 2013
ARRESTIN FROM BOVINE ROD OUTER SEGMENTS
Template:ABSTRACT PUBMED 10219246
Disease
[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
Function
[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
About this Structure
1cf1 is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Hirsch JA, Schubert C, Gurevich VV, Sigler PB. The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell. 1999 Apr 16;97(2):257-69. PMID:10219246
