1p4q: Difference between revisions

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[[Image:1p4q.jpg|left|200px]]<br /><applet load="1p4q" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p4q.jpg|left|200px]]
caption="1p4q" />
 
'''Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain'''<br />
{{Structure
|PDB= 1p4q |SIZE=350|CAPTION= <scene name='initialview01'>1p4q</scene>
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48]
|GENE= CITED2 OR MRG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EP300 OR P300 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1P4Q is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4Q OCA].  
1P4Q is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4Q OCA].  


==Reference==
==Reference==
Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2., Freedman SJ, Sun ZY, Kung AL, France DS, Wagner G, Eck MJ, Nat Struct Biol. 2003 Jul;10(7):504-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12778114 12778114]
Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2., Freedman SJ, Sun ZY, Kung AL, France DS, Wagner G, Eck MJ, Nat Struct Biol. 2003 Jul;10(7):504-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12778114 12778114]
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: protein-protein complex]]
[[Category: protein-protein complex]]


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