1p61: Difference between revisions

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[[Image:1p61.jpg|left|200px]]<br /><applet load="1p61" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p61.jpg|left|200px]]
caption="1p61, resolution 2.21&Aring;" />
 
'''Structure of human dCK complexed with 2'-Deoxycytidine and ADP, P 43 21 2 space group'''<br />
{{Structure
|PDB= 1p61 |SIZE=350|CAPTION= <scene name='initialview01'>1p61</scene>, resolution 2.21&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=DCZ:2'-DEOXYCYTIDINE'>DCZ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxycytidine_kinase Deoxycytidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.74 2.7.1.74]
|GENE= DCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of human dCK complexed with 2'-Deoxycytidine and ADP, P 43 21 2 space group'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1P61 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=DCZ:'>DCZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Deoxycytidine_kinase Deoxycytidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.74 2.7.1.74] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P61 OCA].  
1P61 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P61 OCA].  


==Reference==
==Reference==
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy., Sabini E, Ort S, Monnerjahn C, Konrad M, Lavie A, Nat Struct Biol. 2003 Jul;10(7):513-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12808445 12808445]
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy., Sabini E, Ort S, Monnerjahn C, Konrad M, Lavie A, Nat Struct Biol. 2003 Jul;10(7):513-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12808445 12808445]
[[Category: Deoxycytidine kinase]]
[[Category: Deoxycytidine kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: p-loop]]
[[Category: p-loop]]


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