1p72: Difference between revisions

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[[Image:1p72.jpg|left|200px]]<br /><applet load="1p72" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p72.jpg|left|200px]]
caption="1p72, resolution 2.10&Aring;" />
 
'''Crystal structure of EHV4-TK complexed with Thy and ADP'''<br />
{{Structure
|PDB= 1p72 |SIZE=350|CAPTION= <scene name='initialview01'>1p72</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=THM:THYMIDINE'>THM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21]
|GENE= TK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10331 Equid herpesvirus 4])
}}
 
'''Crystal structure of EHV4-TK complexed with Thy and ADP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1P72 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equid_herpesvirus_4 Equid herpesvirus 4] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=THM:'>THM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P72 OCA].  
1P72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equid_herpesvirus_4 Equid herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P72 OCA].  


==Reference==
==Reference==
Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases., Gardberg A, Shuvalova L, Monnerjahn C, Konrad M, Lavie A, Structure. 2003 Oct;11(10):1265-77. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14527394 14527394]
Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases., Gardberg A, Shuvalova L, Monnerjahn C, Konrad M, Lavie A, Structure. 2003 Oct;11(10):1265-77. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14527394 14527394]
[[Category: Equid herpesvirus 4]]
[[Category: Equid herpesvirus 4]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: p-loop]]
[[Category: p-loop]]


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