1p9u: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1p9u.gif|left|200px]] | [[Image:1p9u.gif|left|200px]] | ||
'''Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs''' | {{Structure | ||
|PDB= 1p9u |SIZE=350|CAPTION= <scene name='initialview01'>1p9u</scene>, resolution 2.37Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CH2:METHYLENE+GROUP'>CH2</scene> and <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene> | |||
|ACTIVITY= | |||
|GENE= ORF1a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11149 Transmissible gastroenteritis virus]) | |||
}} | |||
'''Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs''' | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
1P9U is a [ | 1P9U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Transmissible_gastroenteritis_virus Transmissible gastroenteritis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P9U OCA]. | ||
==Reference== | ==Reference== | ||
Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs., Anand K, Ziebuhr J, Wadhwani P, Mesters JR, Hilgenfeld R, Science. 2003 Jun 13;300(5626):1763-7. Epub 2003 May 13. PMID:[http:// | Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs., Anand K, Ziebuhr J, Wadhwani P, Mesters JR, Hilgenfeld R, Science. 2003 Jun 13;300(5626):1763-7. Epub 2003 May 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12746549 12746549] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Transmissible gastroenteritis virus]] | [[Category: Transmissible gastroenteritis virus]] | ||
| Line 26: | Line 35: | ||
[[Category: tgev]] | [[Category: tgev]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:21:47 2008'' | ||