4hfd: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hfd|  PDB=4hfd  |  SCENE=  }}
===The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to bromoform===


The entry 4hfd is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>  


Authors: Sauguet, L., Howard, R.J., Malherbe, L., Lee, U.S., Corringer, P.J., Harris, R.A., Delarue, M.
==About this Structure==
[[4hfd]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFD OCA].  


Description: The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to bromoform
==Reference==
<references group="xtra"/><references/>
[[Category: Gloeobacter violaceus pcc 7421]]
[[Category: Corringer, P J.]]
[[Category: Delarue, M.]]
[[Category: Harris, R A.]]
[[Category: Howard, R J.]]
[[Category: Lee, U S.]]
[[Category: Malherbe, L.]]
[[Category: Sauguet, L.]]
[[Category: Ion-channel]]
[[Category: Membrane protein]]
[[Category: Pentameric transmembrane channel]]
[[Category: Transport protein]]