1e5g: Difference between revisions
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{{STRUCTURE_1e5g| PDB=1e5g | SCENE= }} | {{STRUCTURE_1e5g| PDB=1e5g | SCENE= }} | ||
===Solution structure of central CP module pair of a pox virus complement inhibitor=== | |||
{{ABSTRACT_PUBMED_11243823}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC]] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b. | |||
==About this Structure== | ==About this Structure== | ||
[[1e5g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[1e5g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus_copenhagen Vaccinia virus copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011243823</ref><references group="xtra"/> | <ref group="xtra">PMID:011243823</ref><references group="xtra"/><references/> | ||
[[Category: Vaccinia virus]] | [[Category: Vaccinia virus copenhagen]] | ||
[[Category: Barlow, P N.]] | [[Category: Barlow, P N.]] | ||
[[Category: Bromek, K.]] | [[Category: Bromek, K.]] | ||
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[[Category: Smith, B O.]] | [[Category: Smith, B O.]] | ||
[[Category: Uhrin, D.]] | [[Category: Uhrin, D.]] | ||
[[Category: Complement inhibitor]] | [[Category: Complement inhibitor]] | ||
Revision as of 11:35, 3 July 2013
Solution structure of central CP module pair of a pox virus complement inhibitor
Template:ABSTRACT PUBMED 11243823
Function
[VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.
About this Structure
1e5g is a 1 chain structure with sequence from Vaccinia virus copenhagen. Full experimental information is available from OCA.
Reference
- Henderson CE, Bromek K, Mullin NP, Smith BO, Uhrin D, Barlow PN. Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. J Mol Biol. 2001 Mar 16;307(1):323-39. PMID:11243823 doi:10.1006/jmbi.2000.4477
