Integrin: Difference between revisions
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<StructureSection load='1zoo' size='400' side='right' caption='Structure of human integrein CD11a I domain dimer complex with Mg+2 and Cl- ions (PDB entry [[1zoo]])' scene=''> | <StructureSection load='1zoo' size='400' side='right' caption='Structure of human integrein CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry [[1zoo]])' scene=''> | ||
'''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix. They are involved in cellular signaling and cell cycle. IGs contain alpha and beta chain. IG subunits span the cell membrane. Both subunits bind divalent cations some of which bind the ligands which interact with IG. Some IGs contain an insertion domain named I domain. | '''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix. They are involved in cellular signaling and cell cycle. IGs contain alpha and beta chain. IG subunits span the cell membrane. Both subunits bind divalent cations some of which bind the ligands which interact with IG. Some IGs contain an insertion domain named I domain. | ||