1pw8: Difference between revisions

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[[Image:1pw8.jpg|left|200px]]<br /><applet load="1pw8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pw8.jpg|left|200px]]
caption="1pw8, resolution 1.30&Aring;" />
 
'''Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin'''<br />
{{Structure
|PDB= 1pw8 |SIZE=350|CAPTION= <scene name='initialview01'>1pw8</scene>, resolution 1.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=H2A:(6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE'>H2A</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4]
|GENE=
}}
 
'''Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PW8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.] with <scene name='pdbligand=H2A:'>H2A</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PW8 OCA].  
1PW8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PW8 OCA].  


==Reference==
==Reference==
Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"., Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA, J Mol Biol. 2005 Jan 21;345(3):521-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15581896 15581896]
Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"., Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA, J Mol Biol. 2005 Jan 21;345(3):521-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15581896 15581896]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: GOL]]
[[Category: GOL]]
[[Category: H2A]]
[[Category: H2A]]
[[Category: antibiotics]]
[[Category: antibiotic]]
[[Category: beta-lactam]]
[[Category: beta-lactam]]
[[Category: enzyme]]
[[Category: enzyme]]
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[[Category: peptidoglycan]]
[[Category: peptidoglycan]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:29:46 2008''
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