1pye: Difference between revisions

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[[Image:1pye.gif|left|200px]]<br /><applet load="1pye" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pye.gif|left|200px]]
caption="1pye, resolution 2.0&Aring;" />
 
'''Crystal structure of CDK2 with inhibitor'''<br />
{{Structure
|PDB= 1pye |SIZE=350|CAPTION= <scene name='initialview01'>1pye</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PM1:[2-AMINO-6-(2,6-DIFLUORO-BENZOYL)-IMIDAZO[1,2-A]PYRIDIN-3-YL]-PHENYL-METHANONE'>PM1</scene>
|ACTIVITY=
|GENE= CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of CDK2 with inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PYE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PM1:'>PM1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PYE OCA].  
1PYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PYE OCA].  


==Reference==
==Reference==
The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines., Hamdouchi C, Keyser H, Collins E, Jaramillo C, De Diego JE, Spencer CD, Dempsey JA, Anderson BD, Leggett T, Stamm NB, Schultz RM, Watkins SA, Cocke K, Lemke S, Burke TF, Beckmann RP, Dixon JT, Gurganus TM, Rankl NB, Houck KA, Zhang F, Vieth M, Espinosa J, Timm DE, Campbell RM, Patel BK, Brooks HB, Mol Cancer Ther. 2004 Jan;3(1):1-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14749470 14749470]
The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines., Hamdouchi C, Keyser H, Collins E, Jaramillo C, De Diego JE, Spencer CD, Dempsey JA, Anderson BD, Leggett T, Stamm NB, Schultz RM, Watkins SA, Cocke K, Lemke S, Burke TF, Beckmann RP, Dixon JT, Gurganus TM, Rankl NB, Houck KA, Zhang F, Vieth M, Espinosa J, Timm DE, Campbell RM, Patel BK, Brooks HB, Mol Cancer Ther. 2004 Jan;3(1):1-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14749470 14749470]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: cyclin-dependent kinase 2]]
[[Category: cyclin-dependent kinase 2]]


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