4abi: Difference between revisions

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===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond===
===Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond===


{{ABSTRACT_PUBMED_22374650}}


==About this Structure==
==About this Structure==

Revision as of 10:41, 14 November 2012

File:4abi.png

Template:STRUCTURE 4abi

Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond

Template:ABSTRACT PUBMED 22374650

About this Structure

4abi is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Tischler M, Nasu D, Empting M, Schmelz S, Heinz DW, Rottmann P, Kolmar H, Buntkowsky G, Tietze D, Avrutina O. Braces for the Peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations. Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3708-12. doi: 10.1002/anie.201108983. , Epub 2012 Feb 28. PMID:22374650 doi:10.1002/anie.201108983

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