1q84: Difference between revisions

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[[Image:1q84.gif|left|200px]]<br /><applet load="1q84" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q84.gif|left|200px]]
caption="1q84, resolution 2.45&Aring;" />
 
'''Crystal structure of the mouse acetylcholinesterase-TZ2PA6 anti complex'''<br />
{{Structure
|PDB= 1q84 |SIZE=350|CAPTION= <scene name='initialview01'>1q84</scene>, resolution 2.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene> and <scene name='pdbligand=TZ4:3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-4-YL]HEXYL]-PHENANTHRIDINIUM'>TZ4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7]
|GENE= ACHE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal structure of the mouse acetylcholinesterase-TZ2PA6 anti complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1Q84 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=P6G:'>P6G</scene> and <scene name='pdbligand=TZ4:'>TZ4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q84 OCA].  
1Q84 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q84 OCA].  


==Reference==
==Reference==
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation., Bourne Y, Kolb HC, Radic Z, Sharpless KB, Taylor P, Marchot P, Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1449-54. Epub 2004 Feb 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14757816 14757816]
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation., Bourne Y, Kolb HC, Radic Z, Sharpless KB, Taylor P, Marchot P, Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1449-54. Epub 2004 Feb 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14757816 14757816]
[[Category: Acetylcholinesterase]]
[[Category: Acetylcholinesterase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: serine esterase]]
[[Category: serine esterase]]


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