1q91: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
[[Image:1q91.gif|left|200px]]<br /><applet load="1q91" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1q91.gif|left|200px]]
caption="1q91, resolution 1.60&Aring;" />
 
'''Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor DPB-T'''<br />
{{Structure
|PDB= 1q91 |SIZE=350|CAPTION= <scene name='initialview01'>1q91</scene>, resolution 1.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=DPB:(S)-1-[2'-DEOXY-3',5'-O-(1-PHOSPHONO)BENZYLIDENE-B-D-THREO-PENTOFURANOSYL]THYMINE'>DPB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5]
|GENE=
}}
 
'''Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor DPB-T'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1Q91 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=DPB:'>DPB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q91 OCA].  
1Q91 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q91 OCA].  


==Reference==
==Reference==
Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors., Rinaldo-Matthis A, Rampazzo C, Balzarini J, Reichard P, Bianchi V, Nordlund P, Mol Pharmacol. 2004 Apr;65(4):860-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15044615 15044615]
Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors., Rinaldo-Matthis A, Rampazzo C, Balzarini J, Reichard P, Bianchi V, Nordlund P, Mol Pharmacol. 2004 Apr;65(4):860-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15044615 15044615]
[[Category: 5'-nucleotidase]]
[[Category: 5'-nucleotidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 25: Line 34:
[[Category: alpha-beta-rossman fold]]
[[Category: alpha-beta-rossman fold]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:37:08 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:34:32 2008''
Retrieved from "https://proteopedia.org/1q91"