1qbv: Difference between revisions

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[[Image:1qbv.jpg|left|200px]]<br /><applet load="1qbv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qbv.jpg|left|200px]]
caption="1qbv, resolution 1.80&Aring;" />
 
'''CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR'''<br />
{{Structure
|PDB= 1qbv |SIZE=350|CAPTION= <scene name='initialview01'>1qbv</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PPX:[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE'>PPX</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QBV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hirudinaria_manillensis Hirudinaria manillensis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PPX:'>PPX</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBV OCA].  
1QBV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudinaria_manillensis Hirudinaria manillensis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBV OCA].  


==Reference==
==Reference==
Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes., Bone R, Lu T, Illig CR, Soll RM, Spurlino JC, J Med Chem. 1998 Jun 4;41(12):2068-75. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9622548 9622548]
Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes., Bone R, Lu T, Illig CR, Soll RM, Spurlino JC, J Med Chem. 1998 Jun 4;41(12):2068-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9622548 9622548]
[[Category: Hirudinaria manillensis]]
[[Category: Hirudinaria manillensis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: thrombin]]
[[Category: thrombin]]


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