4hgk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Shark IgNAR variable domain===

~~The~~ entry ~~4hgk~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>

~~Authors~~: ~~Olland, A~~.O., ~~Kovalenko~~, ~~O.V.~~, ~~Svenson~~, K., ~~King, D~~.

==Function==

[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>

~~Description~~: ~~Shark IgNAR variable domain~~

==About this Structure==

[[4hgk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HGK OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Squalus acanthias]]

[[Category: King, D.]]

[[Category: Kovalenko, O V.]]

[[Category: Olland, A O.]]

[[Category: Svenson, K.]]

[[Category: Human albumin]]

[[Category: Ig-fold]]

[[Category: Immune system]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4hgk|  PDB=4hgk  |  SCENE=  }}
+===Shark IgNAR variable domain===
-The entry 4hgk is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
-Authors: Olland, A.O., Kovalenko, O.V., Svenson, K., King, D.
+==Function==
+[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
-Description: Shark IgNAR variable domain
+==About this Structure==
+[[4hgk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HGK OCA].
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Squalus acanthias]]
+[[Category: King, D.]]
+[[Category: Kovalenko, O V.]]
+[[Category: Olland, A O.]]
+[[Category: Svenson, K.]]
+[[Category: Human albumin]]
+[[Category: Ig-fold]]
+[[Category: Immune system]]