1qmd: Difference between revisions

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[[Image:1qmd.jpg|left|200px]]<br /><applet load="1qmd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qmd.jpg|left|200px]]
caption="1qmd, resolution 2.20&Aring;" />
 
'''CALCIUM BOUND CLOSED FORM ALPHA-TOXIN FROM CLOSTRIDIUM PERFRINGENS'''<br />
{{Structure
|PDB= 1qmd |SIZE=350|CAPTION= <scene name='initialview01'>1qmd</scene>, resolution 2.20&Aring;
|SITE= <scene name='pdbsite=CA1:C-Terminal+Ca+(Membrane+Interactions).+In'>CA1</scene>, <scene name='pdbsite=CA2:C-Terminal+Ca+(Membrane+Interactions).+In'>CA2</scene>, <scene name='pdbsite=CA3:C-Terminal+Ca+(Membrane+Interactions).+In'>CA3</scene>, <scene name='pdbsite=CA4:C-Terminal+Ca+(Membrane+Interactions).+In'>CA4</scene>, <scene name='pdbsite=CA5:C-Terminal+Ca+(Membrane+Interactions).+In'>CA5</scene>, <scene name='pdbsite=CA6:C-Terminal+Ca+(Membrane+Interactions).+In'>CA6</scene>, <scene name='pdbsite=ZN1:Active+Site+Zn.+In+A+Molecule'>ZN1</scene>, <scene name='pdbsite=ZN2:Active+Site+Zn.+In+A+Molecule'>ZN2</scene>, <scene name='pdbsite=ZN3:Active+Site+Zn.+In+B+Molecule'>ZN3</scene> and <scene name='pdbsite=ZN4:Active+Site+Zn.+In+B+Molecule'>ZN4</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phospholipase_C Phospholipase C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.3 3.1.4.3]
|GENE=
}}
 
'''CALCIUM BOUND CLOSED FORM ALPHA-TOXIN FROM CLOSTRIDIUM PERFRINGENS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QMD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phospholipase_C Phospholipase C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.3 3.1.4.3] Known structural/functional Sites: <scene name='pdbsite=CA1:C-Terminal+Ca+(Membrane+Interactions).+In'>CA1</scene>, <scene name='pdbsite=CA2:C-Terminal+Ca+(Membrane+Interactions).+In'>CA2</scene>, <scene name='pdbsite=CA3:C-Terminal+Ca+(Membrane+Interactions).+In'>CA3</scene>, <scene name='pdbsite=CA4:C-Terminal+Ca+(Membrane+Interactions).+In'>CA4</scene>, <scene name='pdbsite=CA5:C-Terminal+Ca+(Membrane+Interactions).+In'>CA5</scene>, <scene name='pdbsite=CA6:C-Terminal+Ca+(Membrane+Interactions).+In'>CA6</scene>, <scene name='pdbsite=ZN1:Active+Site+Zn.+In+A+Molecule'>ZN1</scene>, <scene name='pdbsite=ZN2:Active+Site+Zn.+In+A+Molecule'>ZN2</scene>, <scene name='pdbsite=ZN3:Active+Site+Zn.+In+B+Molecule'>ZN3</scene> and <scene name='pdbsite=ZN4:Active+Site+Zn.+In+B+Molecule'>ZN4</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QMD OCA].  
1QMD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QMD OCA].  


==Reference==
==Reference==
Characterisation of the calcium-binding C-terminal domain of Clostridium perfringens alpha-toxin., Naylor CE, Jepson M, Crane DT, Titball RW, Miller J, Basak AK, Bolgiano B, J Mol Biol. 1999 Dec 3;294(3):757-70. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10610794 10610794]
Characterisation of the calcium-binding C-terminal domain of Clostridium perfringens alpha-toxin., Naylor CE, Jepson M, Crane DT, Titball RW, Miller J, Basak AK, Bolgiano B, J Mol Biol. 1999 Dec 3;294(3):757-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10610794 10610794]
[[Category: Clostridium perfringens]]
[[Category: Clostridium perfringens]]
[[Category: Phospholipase C]]
[[Category: Phospholipase C]]
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[[Category: zinc phospholipase c]]
[[Category: zinc phospholipase c]]


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