1gwg: Difference between revisions
New page: left|200px<br /> <applet load="1gwg" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gwg, resolution 2.01Å" /> '''TRI-IODIDE DERIVATI... |
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==About this Structure== | ==About this Structure== | ||
1GWG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]] with IOD and CD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWG OCA]]. | 1GWG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]] with IOD and CD as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: CD1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWG OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: multigene family]] | [[Category: multigene family]] | ||
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Revision as of 06:28, 30 October 2007
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TRI-IODIDE DERIVATIVE OF APOFERRITIN
Overview
A series of experiments performed at Cu Kalpha wavelength on in-house, X-ray equipment are presented which investigate two possibilities for, enhancing the experimental phasing signal by means of (i) triiodide/iodide, soaks using KI/I(2) and (ii) combinations of counter-ions introduced using, the short cryosoak method. Triiodide-derivative crystal structures for, five test proteins have been refined and reveal that iodine can bind as, polyiodide and single iodide ions through hydrophobic and hydrogen-bonding, interactions both at the molecular surface and in intramolecular and, intermolecular cavities. In three cases, the structures could be, automatically determined with autoSHARP using in-house SAD and SIRAS data., The investigation of combinatorial counter-ion replacement using ... [(full description)]
About this Structure
1GWG is a [Single protein] structure of sequence from [Equus caballus] with IOD and CD as [ligands]. Structure known Active Site: CD1. Full crystallographic information is available from [OCA].
Reference
Triiodide derivatization and combinatorial counter-ion replacement: two methods for enhancing phasing signal using laboratory Cu Kalpha X-ray equipment., Evans G, Bricogne G, Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):976-91. Epub, 2002 May 29. PMID:12037300
Page seeded by OCA on Tue Oct 30 08:33:28 2007
