1qv6: Difference between revisions

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[[Image:1qv6.jpg|left|200px]]~~<br /><applet load~~="1qv6~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1qv6.jpg|left|200px]]

~~caption="~~1qv6, resolution 1.80Å" />

'''HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL'''~~<br />~~

{{Structure

|PDB= 1qv6 |SIZE=350|CAPTION= <scene name='initialview01'>1qv6</scene>, resolution 1.80Å

|SITE=

|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=24B:(2,4-DIFLUOROPHENYL)METHANOL'>24B</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]

|GENE=

}}

'''HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL'''

==Overview==

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==About this Structure==

1QV6 is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] ~~with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NAD:'>NAD</scene>, <scene name='pdbligand=24B:'>24B</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia~~.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QV6 OCA].

1QV6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QV6 OCA].

==Reference==

Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase., LeBrun LA, Park DH, Ramaswamy S, Plapp BV, Biochemistry. 2004 Mar 23;43(11):3014-26. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15023053 15023053]

Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase., LeBrun LA, Park DH, Ramaswamy S, Plapp BV, Biochemistry. 2004 Mar 23;43(11):3014-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15023053 15023053]

[[Category: Alcohol dehydrogenase]]

[[Category: Equus caballus]]

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[[Category: nicotinamide coenzyme]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 14~~:44:03 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:43:10 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1qv6.jpg|left|200px]]<br /><applet load="1qv6" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1qv6.jpg|left|200px]]
-caption="1qv6, resolution 1.80&Aring;" />
-'''HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL'''<br />
+ {{Structure
+|PDB= 1qv6 |SIZE=350|CAPTION= <scene name='initialview01'>1qv6</scene>, resolution 1.80&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=24B:(2,4-DIFLUOROPHENYL)METHANOL'>24B</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
+|GENE=
+}}
+'''HORSE LIVER ALCOHOL DEHYDROGENASE HIS51GLN/LYS228ARG MUTANT COMPLEXED WITH NAD+ AND 2,4-DIFLUOROBENZYL ALCOHOL'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-QV6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NAD:'>NAD</scene>, <scene name='pdbligand=24B:'>24B</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QV6 OCA].
+QV6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QV6 OCA].
 ==Reference==
-Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase., LeBrun LA, Park DH, Ramaswamy S, Plapp BV, Biochemistry. 2004 Mar 23;43(11):3014-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15023053 15023053]
+Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase., LeBrun LA, Park DH, Ramaswamy S, Plapp BV, Biochemistry. 2004 Mar 23;43(11):3014-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15023053 15023053]
 [[Category: Alcohol dehydrogenase]]
 [[Category: Equus caballus]]
@@ Line 30: / Line 39: @@
 [[Category: nicotinamide coenzyme]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:44:03 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:43:10 2008''