1qx4: Difference between revisions

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[[Image:1qx4.jpg|left|200px]]<br /><applet load="1qx4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1qx4.jpg|left|200px]]
caption="1qx4, resolution 1.8&Aring;" />
 
'''Structrue of S127P mutant of cytochrome b5 reductase'''<br />
{{Structure
|PDB= 1qx4 |SIZE=350|CAPTION= <scene name='initialview01'>1qx4</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE DINUCLEOTIDE'>FAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-b5_reductase Cytochrome-b5 reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.2.2 1.6.2.2]
|GENE= DIA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Structrue of S127P mutant of cytochrome b5 reductase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1QX4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=FAD:'>FAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Cytochrome-b5_reductase Cytochrome-b5 reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.2.2 1.6.2.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QX4 OCA].  
1QX4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QX4 OCA].  


==Reference==
==Reference==
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site., Bewley MC, Davis CA, Marohnic CC, Taormina D, Barber MJ, Biochemistry. 2003 Nov 18;42(45):13145-51. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14609324 14609324]
The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site., Bewley MC, Davis CA, Marohnic CC, Taormina D, Barber MJ, Biochemistry. 2003 Nov 18;42(45):13145-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14609324 14609324]
[[Category: Cytochrome-b5 reductase]]
[[Category: Cytochrome-b5 reductase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: methemoglobinemia]]
[[Category: methemoglobinemia]]


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