4hl8: Difference between revisions
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{{STRUCTURE_4hl8| PDB=4hl8 | SCENE= }} | |||
===Re-refinement of the vault ribonucleoprotein particle=== | |||
{{ABSTRACT_PUBMED_19150846}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MVP_RAT MVP_RAT]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | |||
==About this Structure== | |||
[[4hl8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HL8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:019150846</ref><references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Casanas, A.]] | |||
[[Category: Fita, I.]] | |||
[[Category: Guerra, P.]] | |||
[[Category: Pous, J.]] | |||
[[Category: Querol-Audi, J.]] | |||
[[Category: Tanaka, H.]] | |||
[[Category: Tsukihara, T.]] | |||
[[Category: Verdaguer, V.]] | |||
[[Category: 9 repeat domain]] | |||
[[Category: Cytoplasmic]] | |||
[[Category: Protein-protein complex]] | |||
[[Category: Ribonucleoprotein]] | |||
[[Category: Structural protein]] | |||