1r5k: Difference between revisions

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[[Image:1r5k.gif|left|200px]]<br /><applet load="1r5k" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1r5k.gif|left|200px]]
caption="1r5k, resolution 2.70&Aring;" />
 
'''Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638'''<br />
{{Structure
|PDB= 1r5k |SIZE=350|CAPTION= <scene name='initialview01'>1r5k</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GW5:(2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID'>GW5</scene>
|ACTIVITY=
|GENE= ESR1 OR NR3A1 OR ESR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1R5K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GW5:'>GW5</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5K OCA].  
1R5K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R5K OCA].  


==Reference==
==Reference==
Structural basis for an unexpected mode of SERM-mediated ER antagonism., Wu YL, Yang X, Ren Z, McDonnell DP, Norris JD, Willson TM, Greene GL, Mol Cell. 2005 May 13;18(4):413-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15893725 15893725]
Structural basis for an unexpected mode of SERM-mediated ER antagonism., Wu YL, Yang X, Ren Z, McDonnell DP, Norris JD, Willson TM, Greene GL, Mol Cell. 2005 May 13;18(4):413-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15893725 15893725]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: helical sandwich]]
[[Category: helical sandwich]]


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