1rdq: Difference between revisions

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[[Image:1rdq.gif|left|200px]]<br /><applet load="1rdq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rdq.gif|left|200px]]
caption="1rdq, resolution 1.26&Aring;" />
 
'''Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase'''<br />
{{Structure
|PDB= 1rdq |SIZE=350|CAPTION= <scene name='initialview01'>1rdq</scene>, resolution 1.26&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= PRKACA, PKACA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RDQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ADP:'>ADP</scene>, <scene name='pdbligand=ATP:'>ATP</scene>, <scene name='pdbligand=MRD:'>MRD</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RDQ OCA].  
1RDQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RDQ OCA].  


==Reference==
==Reference==
Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism., Yang J, Ten Eyck LF, Xuong NH, Taylor SS, J Mol Biol. 2004 Feb 13;336(2):473-87. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14757059 14757059]
Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism., Yang J, Ten Eyck LF, Xuong NH, Taylor SS, J Mol Biol. 2004 Feb 13;336(2):473-87. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14757059 14757059]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: camp-dependent protein kinase]]
[[Category: camp-dependent protein kinase]]
[[Category: catalytic mechanism]]
[[Category: catalytic mechanism]]
[[Category: two nucleotide states]]
[[Category: two nucleotide state]]


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