1rev: Difference between revisions

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[[Image:1rev.gif|left|200px]]<br /><applet load="1rev" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rev.gif|left|200px]]
caption="1rev, resolution 2.6&Aring;" />
 
'''HIV-1 REVERSE TRANSCRIPTASE'''<br />
{{Structure
|PDB= 1rev |SIZE=350|CAPTION= <scene name='initialview01'>1rev</scene>, resolution 2.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=TB9:4-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE'>TB9</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= HIV-1 POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''HIV-1 REVERSE TRANSCRIPTASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1REV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=TB9:'>TB9</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REV OCA].  
1REV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REV OCA].  


==Reference==
==Reference==
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design., Ren J, Esnouf R, Hopkins A, Ross C, Jones Y, Stammers D, Stuart D, Structure. 1995 Sep 15;3(9):915-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8535785 8535785]
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design., Ren J, Esnouf R, Hopkins A, Ross C, Jones Y, Stammers D, Stuart D, Structure. 1995 Sep 15;3(9):915-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8535785 8535785]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: MG]]
[[Category: MG]]
[[Category: TB9]]
[[Category: TB9]]
[[Category: aids]]
[[Category: aid]]
[[Category: aspartyl protease]]
[[Category: aspartyl protease]]
[[Category: endonuclease]]
[[Category: endonuclease]]
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[[Category: polyprotein]]
[[Category: polyprotein]]


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