1rf2: Difference between revisions

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[[Image:1rf2.jpg|left|200px]]<br /><applet load="1rf2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rf2.jpg|left|200px]]
caption="1rf2, resolution 1.35&Aring;" />
 
'''Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV4'''<br />
{{Structure
|PDB= 1rf2 |SIZE=350|CAPTION= <scene name='initialview01'>1rf2</scene>, resolution 1.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BV4:1,3-BIS-([3-[3-[3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO-3,4-DIOXO-CYCLOBUTENYL]-AMINO-PROPOXY-ETHOXY-ETHOXY]-PROPYL-]AMINO-CARBONYLOXY)-2-AMINO-PROPANE'>BV4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene> and <scene name='pdbligand=PGE:TRIETHYLENE GLYCOL'>PGE</scene>
|ACTIVITY=
|GENE= ctxB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])
}}
 
'''Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV4'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RF2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae] with <scene name='pdbligand=BV4:'>BV4</scene>, <scene name='pdbligand=TRS:'>TRS</scene> and <scene name='pdbligand=PGE:'>PGE</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RF2 OCA].  
1RF2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RF2 OCA].  


==Reference==
==Reference==
Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer., Pickens JC, Mitchell DD, Liu J, Tan X, Zhang Z, Verlinde CL, Hol WG, Fan E, Chem Biol. 2004 Sep;11(9):1205-15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15380181 15380181]
Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer., Pickens JC, Mitchell DD, Liu J, Tan X, Zhang Z, Verlinde CL, Hol WG, Fan E, Chem Biol. 2004 Sep;11(9):1205-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15380181 15380181]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
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[[Category: toxin]]
[[Category: toxin]]


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