1rrv: Difference between revisions

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[[Image:1rrv.gif|left|200px]]<br /><applet load="1rrv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1rrv.gif|left|200px]]
caption="1rrv, resolution 2.0&Aring;" />
 
'''X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.'''<br />
{{Structure
|PDB= 1rrv |SIZE=350|CAPTION= <scene name='initialview01'>1rrv</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=DVV:DESVANCOSAMINYL+VANCOMYCIN'>DVV</scene>, <scene name='pdbligand=TYD:THYMIDINE-5'-+DIPHOSPHATE'>TYD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= gtfD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 Amycolatopsis orientalis])
}}
 
'''X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1RRV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis] with <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=DVV:'>DVV</scene>, <scene name='pdbligand=TYD:'>TYD</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRV OCA].  
1RRV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRV OCA].  


==Reference==
==Reference==
Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands., Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM, Biochemistry. 2004 May 11;43(18):5170-80. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15122882 15122882]
Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands., Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM, Biochemistry. 2004 May 11;43(18):5170-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15122882 15122882]
[[Category: Amycolatopsis orientalis]]
[[Category: Amycolatopsis orientalis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: rossmann fold]]
[[Category: rossmann fold]]


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